Charles Wreford-Brown was born in Bristol on 9th October 1866. He was educated at Charterhouse School and at this time public schools were pioneering the game of football. He was a talented sportsman and played football and cricket for Oxford University.
After leaving university he played cricket for he played cricket for Gloucestershire and football for the Old Carthusians.
On the 2nd March 1889 Wreford-Brown won his first international cap playing at centre-half for England against Ireland. England won 6-1.
Wreford-Brown was appointed to the council of the Football Association in 1892 as the representative of Old Carthusians. He won his second cap for England against Wales in 1894. This time he was appointed captain and played an important role in the 5-1 victory.
Wreford-Brown was also captain the following year. After a three year gap he was recalled to play for England against Scotland and helped his country to a 3-1 victory.
After retiring from playing Wreford-Brown represented Oxford University on the FA Council. He also served as a vice-president of the FA between 1941 and 1951.
Charles Wreford-Brown died on 26th November 1951.