Mohammed Neguib was born in Khartoum in 1901. He was educated at the Cairo Military Academy and during the Second World War he joined the Free Officers Movement.

The failed 1948 Palestine campaign reinforced Neguib's view that the government of Farouk I was inefficient and corrupt. In July 1952, General Neguib and Colonel Gamal Abdel Nasser forced Farouk to abdicate. After the Egyptian Revolution Neguib became commander-in-chief, prime minister and president of the republic whereas Nasser held the post of Minister of the Interior.

The young officers considered Neguib to be too moderate and in November 1954 he resigned as president and retired from public life.

Mohammed Neguib died in 1984.