Charles Crenshaw was born in Texas. He received his BS from Southern Methodist University and his MS from East Texas State University. He worked on his Ph.D. at Baylor University Graduate Research Institute in 1957 and, in 1960 received a M.D. from the University of Texas Southwestern Medical School. He then became the resident physician in Parkland Hospital in Dallas.
When John F. Kennedy was shot on 22nd November, 1963, he was taken to the hospital and was treated by Dr. Malcolm Perry. Perry performed a tracheotomy over the small wound in Kennedy's throat, therefore inadvertently destroying crucial evidence concerning the direction of the bullet that hit the president. At the press conference that followed the death of Kennedy, Perry stated that he thought the throat hole looked like an entrance wound.
Crenshaw also treated Kennedy at Parkland Hospital. He later stated: "Two wounds were visible. There was a small, round opening in the front of the midline of the throat. This became the site of Dr. Malcolm Perry's tracheotomy incision. In the occipito-parietal region at the right rear of the head, there was an avulsive wound nearly as large as a fist.... I considered the throat wound to be an entrance wound and the large head wound to be an exit wound. Along with many of my Parkland colleagues, I believed at the time that President Kennedy had been hit twice from the front."
The author of JFK: Conspiracy of Silence (1992), Crenshaw, along with Robert Livingston, David Mantik, Ronald F. White and Jack White, contributed to Assassination Science (edited by James H. Fetzer). Crenshaw is also co-author with Gary Shaw of Trauma Room One (2001).
Crenshaw eventually became Professor of Clinical Surgery at Southwestern Medical School in Dallas. He later worked at the Department of Surgery at John Peter Smith Hospital at Fort Worth.
Charles Crenshaw, died at his home in Fort Worth, Texas on 15th November, 2001.